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Retin-A (tretinoin topical) is used to treat acne that did not respond to other methods of treatment. It helps to control acne but cannot cure this skin condition. Tretinoin is available in gel, cream and topical liquid. How you should use this medicine depends on the condition of your acne and your general health condition. It can be used daily or every 3 days. It’s therefore important that you listen carefully to your doctor’s instructions. Do not share your medicine with other people as this drug should be available to people who have a prescription from their health care provider and really need this kind of treatment.